Glossary

A large natural product, which is produced by the decomposition of organic water and is common in surface waters.

The classical method for fractionating the humic colloids that disperse in the sodium hydroxide extract is to acidify the suspension with sulphuric or hydrochloric acid, which causes a part of the dispersed organic matter to precipitate. The part that stays in solution is known as fulvic acid, the one that precipitates out is known as humic acid, and the part of the organic matter which does not disperse in the alkali but remains in the soil, is known as humin.

A device for adding moisture to room air.

The production of antibody by B cells of the immune system in response to the presence of a foreign antigen.

An adult-onset disease characterized by progressive mental and physical deterioration; it is caused by an inherited dominant gene mutation.

Heating, Ventilation, and Air Conditioning

Heating and Ventilating Contractors Association (United Kingdom)

Home Ventilating Institute

Hardware

Hazardous Waste Action Coalition

Hazardous Waste Management

Hazardous Waste Treatment Council

1. The offspring of two parents that are genetically different. A cross between two genetically unlike individuals.2. A heteroduplex DNA or DNA-RNA molecule.

Co-existence of paper and electronic record and signature components. Examples include combinations of paper (or other nonelectronic media) and electronic records, paper records and electronic signatures, or handwritten signatures executed to electronic records.

One that uses both non-electronic (e.g., paper or microfiche) and digital/electronic output media. Similarly, a hybrid record is a record comprising at least two components stored on different media, typically electronic and paper. An example of a hybrid record would be an electronic record that is printed and approved on paper with a handwritten wet ink signature.

Combination of electronic and paper records, common in today’s analytical labs, in which raw data is recorded electronically to reconstruct the analysis, but the final results are printed and signed on paper. FDA does not prohibit hybrid systems but has expressed some concerns about their usefulness.

The process of joining two complementary strands of DNA or one each of DNA and RNA to form a double-stranded molecule.

A hybrid cell resulting from the fusion of a specific antibody producing spleen cell with a myeloma cell. The hybrid cell has the growth characteristics of the myeloma component and the antibody secreting characteristics of the spleen cell and will multiply to become a source of large quantities of pure, monoclonal antibody.

An immortalized cell line (usually derived by fusing B-lymphocyte cells with myeloma tumor cells) that secretes a desirable protein, typically a monoclonal antibody.

Organic compounds containing only carbon and hydrogen. Sometimes broadened to include compounds or mixtures of compounds with small amounts of oxygen also.

Organic compounds containing only carbon and hydrogen. Sometimes broadened to include compounds or mixtures of compounds with small amounts of oxygen also.

A colorless, heavy, strongly oxidizing, unstable liquid used principally in aqueous solutions as an antiseptic, bleaching agent, oxidizing agent, and laboratory reagent. In the vapor phase, as an airborne sterilant.

A chemical reaction between water and organic compounds, particularly esters, ketones, and alcohols. This reaction can lead to breakdown of some proteins.

Having a strong affinity for water; attracting, dissolving in, or absorbing water; readily absorbing moisture; having strong polar groups that readily interact with water. Its opposite, hydrophobic.